Salmon DNA (Polynucleotide) Injections & Microneedling at Santosha Aesthetics

Pharmaceutical-grade PN — not your average Salmon DNA

At Santosha Aesthetics, we use pharmaceutical-grade Polynucleotides (PN) — sterile, injectable, high molecular weight, and sourced from certified Korean laboratories. Unlike diluted PDRN, our PN delivers deeper, longer-lasting skin regeneration.

What Are Polynucleotides (PN)?

Polynucleotides are long-chain DNA fragments derived from salmon sperm — a naturally biocompatible source with a structure nearly identical to human DNA. When injected, PN molecules act as a biological scaffold that activates fibroblasts (your collagen-producing cells), promotes tissue repair, reduces inflammation, and deeply hydrates from within.

The key difference between PN and PDRN is potency and molecular weight. Our pharmaceutical-grade PN is high molecular weight, undiluted, and sterile — delivering a significantly more powerful regenerative stimulus. This is the same class of treatment generating results in South Korea and across Europe, now available in Beverly Hills.

Who Is This Treatment For?

Polynucleotide treatments are ideal for anyone experiencing:

  • Active acne or post-acne scarring
  • Enlarged or visible pores
  • Fine lines and early signs of aging
  • Dull, uneven, or dehydrated skin
  • Textural irregularities or general scarring
  • Skin that looks tired despite a good skincare routine
  • Under eye bags, dark circles, and crepey under-eye skin
  • Those wanting to tighten, lift, and help even skin tone

✦ Great Add-On: RF Skin Tightening — Radiofrequency energy is an ideal complement to PN treatments. RF heats the deep dermis to stimulate collagen contraction and increase cellular receptivity, priming your skin to better absorb and amplify Polynucleotide results. Ask Panteha about adding RF to your PN treatment plan.

PN works on all skin types and tones, and can be safely used on the face, neck, décolletage, and hands.

Two Ways to Deliver Polynucleotides

Panteha customizes every treatment to your skin’s needs — injections, microneedling, or a layered combination.

Polynucleotide Injections

Using a fine needle, Panteha precisely microinjects pharmaceutical-grade PN directly into the dermis at targeted depths — ideal for under-eye hollows, acne scars, deep pores, or areas of skin laxity. Can be layered with fillers, biostimulators, or wrinkle treatments.

Pricing: Based on area and treatment plan. Book a consultation.

Microneedling with Polynucleotides

Microneedling creates thousands of micro-channels, and we immediately infuse PN for maximum absorption — amplifying both the collagen induction and the regenerative power of PN. Exceptionally effective for acne scars, pore reduction, texture, and brightening.

Package of 3 sessions: $999

How Many Sessions Will I Need?

Results depend on your skin’s starting point. As a general guide:

  • Maintenance / skin quality improvement: 3 sessions
  • Active acne, larger pores, or general scarring: 4–6 sessions
  • Deep acne scars or aged skin with significant texture concerns: 4–6 sessions

Sessions are typically spaced 3–4 weeks apart. Most patients see visible improvement after their second treatment, with optimal results appearing 6–8 weeks after completing the full series.

Why Choose Santosha Aesthetics?

  • Pharmaceutical-grade PN — sterile, injectable, high molecular weight, not diluted
  • Sourced from certified Korean laboratories
  • Administered by Panteha Partovi, MPA, PA-C — 12+ years of clinical experience
  • Customized treatment plans — PN layered with fillers, biostimulators, and wrinkle treatments
  • Located in Beverly Hills — serving Los Angeles and surrounding areas

Frequently Asked Questions

What is the difference between Salmon DNA and PDRN?
PDRN uses shorter, lighter DNA fragments that are often diluted — milder effect and shorter duration. Our pharmaceutical-grade PN uses longer, higher molecular weight chains that form a 3D structure in the dermis, providing deeper, more sustained collagen stimulation. Sterile, undiluted, and injectable — significantly more potent than typical PDRN products.
Is Polynucleotide treatment safe?
Yes. Polynucleotides are highly biocompatible — the molecular structure of salmon DNA closely resembles human DNA. Our product is manufactured to pharmaceutical, sterile-injectable standards. Side effects are minimal: temporary redness, mild swelling, or bruising at injection sites.
How long do Polynucleotide results last?
Results from a full series can last 12–18 months, as the treatment stimulates your own collagen production rather than just adding volume. Many patients do a maintenance session every 6–12 months.
Can Polynucleotides be combined with other treatments?
Absolutely — PN pairs beautifully with dermal fillers, biostimulators (Sculptra, Radiesse), and wrinkle treatments. Panteha specializes in layered plans that address volume, structure, and skin quality simultaneously.
How much do Polynucleotide treatments cost in Beverly Hills?
Microneedling with PN: 3 sessions for $999. Injection pricing depends on the treatment area and plan. Call (310) 740-9373 or book a consultation for a personalized quote.
How is this different from regular microneedling?
Standard microneedling stimulates collagen through micro-injuries. Adding PN immediately floods those channels with a powerful regenerative signal — significantly amplifying results. The combination treats texture, scars, pores, and skin quality more effectively than either treatment alone.
Is there downtime after Polynucleotide treatment?
Minimal. After injections: mild redness or swelling for 24–48 hours. After microneedling with PN: 1–2 days of redness similar to a mild sunburn. Most patients return to normal activities the next day.

Ready to Transform Your Skin?

Book a consultation with Panteha at Santosha Aesthetics in Beverly Hills and discover how pharmaceutical-grade Polynucleotide treatments can rebuild your skin from within.

📍 8500 Wilshire Blvd, Suite 615, Beverly Hills, CA 90211  |  📞 (310) 740-9373